Autoimmune diseases are highly risky and can be fatal in the long run. They are caused by the body’s inability to distinguish between the internalAutoimmune diseases are highly risky and can be fatal in the long run. They are caused by the body’s inability to distinguish between the internal and foreign attackers and thus, the body’s capability to fight off these diseases decreases. However, women are more prone to every autoimmune disease than men and there are plenty of speculations and research on this topic as to why this happens. We are going to explore a few possibilities and reasons behind this phenomenon in this article.
The biological difference in the male and female bodies is evident in the fact that both physical bodies react and respond to certain diseases in a specific way. That is, according to some experts, due to the evolutionary behavior of both bodies and how they have been trained by many internal and external factors for reacting or responding to issues like diseases, physical dangers, and many such things. Considering all these facts, the experts and researchers have found a few reasons for this variation in response to every autoimmune disease in men and women.
For instance, some consider the difference of hormonal changes, growth patterns, and their functions in male and female bodies. These are highly responsible for making the female internal system quite vulnerable to autoimmune diseases. In this regard, however, the female sex hormones play a vital role in making the body vulnerable to such diseases.
Similarly, others blame microchimerism or the genetic transfer of cells from one body to another for autoimmune diseases in female bodies. This means that experts believe that the female body is more vulnerable to such diseases and they are also transferred to their children (largely females) from the mothers. Thus, the X-chromosome is to be held responsible for being more prone to catching such diseases than the Y-chromosome.
Due to the lack of control over the causation of such autoimmunity diseases, a large portion of adult and middle-aged women suffer. In fact, a huge number of them die annually due to these diseases. Although there has been a good amount of research on finding out the exact reasons behind this vulnerability among women to catch autoimmunity diseases, the experts have still been unable to find the root cause of it.
However, the ongoing research highlights the role of antibodies and B-cells. This means that the evolutionary process has somehow created a conserved B-cell process among women that keeps the body’s immunity system quite vulnerable to many diseases. This does not mean that the female body is “weaker”, it simply means that evolution has left some loopholes in creating a perfect autoimmune disease fighting system.
Besides, external factors like emotional, psychological, social, and environmental, are also somehow responsible for the further weakening of the female immunity system. Simply put, the more fearful and conserved a female body and mind remain, the more its immunity system remains alike.
However, there are many contrasting opinions by the experts as well. For instance, some say that the linkage between autoimmunity diseases and the B-cells can also be found very clearly in males as well. Thus, the argument remains contradictory to the general findings in which the male bodies also respond to these diseases in a similar fashion.
Keeping in mind both arguments, one can only speculate the possible reasons behind frequent and prominent female vulnerability towards every autoimmune disease, as compared to males. The ratio in females, though, remains higher than in males which indicates the functions of varying hormonal and cellular differences in both sexes. Thus, the frequency and intensity of acquiring autoimmunity diseases in women are directly proportional to their internal changes in hormones, immunity cells, microchimerism, and external environmental factors as well.